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The Modification of Diet in Renal Disease (MDRD) equation is a formula used to estimate glomerular filtration rate (GFR), which is a measure of kidney function. The equation uses a person's creatinine level, age, sex, and race to estimate their GFR.
The MDRD equation was developed in the 1990s by a group of researchers led by Dr. John Eckfeldt, with the aim to improve the accuracy of GFR estimation in people with chronic kidney disease (CKD). It was also validated in a large population of patients with CKD and found to be more accurate than previous equations. The MDRD formula was created by Andrew S. Levey in 1999, an American nephrologist and Professor of Medicine in the Tufts University School of Medicine, and which is a widely recognized authority on clinical practice guidelines in CKD that has contributed to guideline development, implementation, quality improvement and public policy in this area.
The MDRD equation is widely used in clinical practice and research as it provides a more accurate estimate of GFR in people with CKD, particularly in those with a creatinine level between 1.2 and 4 mg/dL. It is also useful in patients with different races, which is not taken into account in the Cockcroft-Gault equation.
It's important to note that the MDRD equation is not recommended for use in people with normal kidney function, and it's not suitable for use in children. Also, is not recommended for use in critically ill patients, or in those with creatinine levels below or above certain limits.
The MDRD equation provides a more accurate estimate of GFR in people with CKD, particularly in those with a creatinine level between 1.2 and 4 mg/dL.
Please note that this equation is not recommended for use in critically ill patients, or in those with creatinine levels below or above certain limits. Also, the MDRD formula does not reflect GFR in ESRD patients. The references suggest that using equations that take into account plasma creatinine levels to estimate GFR, like the MDRD equation, is not a reliable practice for patients with end-stage renal disease (ESRD) because the muscle mass affects the plasma creatinine in a greater measure than the kidney function..
The Modification of Diet in Renal Disease (MDRD) equation is a formula used to estimate glomerular filtration rate (GFR), which is a measure of kidney function. The equation uses a person's creatinine level, age, sex, and race to estimate their GFR.
The MDRD equation was developed in the 1990s by a group of researchers led by Dr. John Eckfeldt, with the aim to improve the accuracy of GFR estimation in people with chronic kidney disease (CKD). It was also validated in a large population of patients with CKD and found to be more accurate than previous equations. The MDRD formula was created by Andrew S. Levey in 1999, an American nephrologist and Professor of Medicine in the Tufts University School of Medicine, and which is a widely recognized authority on clinical practice guidelines in CKD that has contributed to guideline development, implementation, quality improvement and public policy in this area.
The MDRD equation is widely used in clinical practice and research as it provides a more accurate estimate of GFR in people with CKD, particularly in those with a creatinine level between 1.2 and 4 mg/dL. It is also useful in patients with different races, which is not taken into account in the Cockcroft-Gault equation.
It's important to note that the MDRD equation is not recommended for use in people with normal kidney function, and it's not suitable for use in children. Also, is not recommended for use in critically ill patients, or in those with creatinine levels below or above certain limits.
MDRD, Modification, Lifestyle, diet, renal, disease, 1999The Modification of Diet in Renal Disease (MDRD) glomerular filtration rate calculatorMDRD GFR calculator0000
