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ABCD3 Score Calculator: Enhancing Stroke Risk Assessment after TIA

The ABCD3/-I Scores

The ABCD3 Score:

The ABCD3 score is a clinical risk stratification tool used to assess the short-term risk of stroke following a transient ischemic attack (TIA). It evaluates five parameters:

  1. Age (A)
  2. Blood pressure (B)
  3. Clinical features (C)
  4. Duration of TIA (D)
  5. Diabetes (D)
  6. Dual TIA (D)

Each parameter is assigned a score ranging from 0 to 2, with a total score ranging from 0 to 7. The higher the score, the greater the risk of stroke. The ABCD3 score helps clinicians identify individuals who require urgent evaluation and intervention to prevent future strokes.

ABCD 3-I Score:

The 3-I score is an enhanced version of the ABCD3 score that incorporates additional parameters for risk assessment. In addition to the original ABCD3 parameters, the 3-I score includes two more parameters:

  • Abnormal DWI (diffusion-weighted image)
  • Ipsilateral stenosis of the carotid artery (I)

These new parameters are associated with an increased risk of stroke following a TIA. By considering these additional factors, the 3-I score provides a more comprehensive risk assessment, allowing for better prediction of stroke risk and potentially influencing treatment decisions.

Use:

Both the ABCD3 and 3-I scores are used by healthcare professionals to evaluate the risk of stroke in individuals who have experienced a transient ischemic attack. These scores assist in the identification of patients who may benefit from urgent intervention, such as initiation of antiplatelet therapy, anticoagulation, or expedited referral to a specialist. The scores help guide clinical decision-making, enabling healthcare providers to prioritize interventions and optimize patient care based on their individual risk profiles.

It's important to note that these scoring systems are tools to aid in risk assessment and should be used in conjunction with clinical judgment and other diagnostic tests. Healthcare professionals will consider various factors, including patient history, physical examination findings, and additional investigations, to make informed decisions regarding the management and treatment of patients at risk of stroke following a TIA.

Last update: 29 Jun 2023 00:06
Statistical data taken from the following studies: [1], [2], [6]
Performance and further reading

The new ABCD 3 and ABCD 3-I Scores

While the original ABCD2 score has been extensively used and validated in numerous studies, subsequent research has identified additional factors that strongly correlate with the risk of developing an ischemic stroke. These factors have been incorporated into the newer ABCD3 and 3-I Scores. These updated scoring systems enable improved risk stratification and prediction of stroke following a transient ischemic attack (TIA). Notably, the ABCD3 and 3-I Scores exhibit higher sensitivity and offer enhanced long-term stroke risk prediction, with a good correlation observed up to 3 years after a TIA. [1] Here's some information on when and how to use them:

  1. The ABCD3 Score:
    • The ABCD3 score is an extension of the ABCD2 score and includes additional factors to further refine stroke risk assessment.
    • In addition to the factors considered in the ABCD2 score, the ABCD3 score incorporates the presence of a previous TIA event within a week of the second one (dual TIA) (2 points).
    • The ABCD3 score provides a more detailed risk assessment and can help identify patients at higher risk of stroke after a TIA.
    • Similar to the ABCD2 score, higher ABCD3 scores indicate a greater risk of stroke.
    • Healthcare professionals can use the ABCD3 instead of the ABCD2 score to enhance risk stratification and inform treatment decisions, as the new score includes all the parameters also taken into account in the previous score.
  2. The 3-I Score:
    • The 3-I score is another scoring system used for risk prediction following a TIA.
    • The 3-I score incorporates three components: Clinical features, Imaging findings, and Intervention.
    • The Clinical features component assesses factors such as age, blood pressure, and symptoms duration.
    • The Imaging findings component considers the presence of carotid stenosis or an abnormal DWI (Diffusion weighted imaging) on an MRI Scan.
    • The Intervention component evaluates whether immediate intervention, such as carotid endarterectomy or stenting, is planned or indicated.
    • The 3-I score provides a comprehensive assessment of stroke risk, incorporating both clinical and imaging factors.
    • Healthcare professionals can utilize the 3-I score in conjunction with other scoring systems to guide treatment decisions, including the need for urgent interventions.

Word of advice

When determining which scoring system to use, healthcare professionals should consider the available evidence, local guidelines, and institutional protocols. Clinical judgment and expertise are crucial in interpreting the scores and making informed decisions regarding patient management.

It's important to note that while the ABCD2, ABCD3, and 3-I scores are valuable tools, they are not the sole determining factors in assessing stroke risk after a TIA. A comprehensive evaluation, including patient history, physical examination, imaging studies, and consultation with specialists, is essential for appropriate risk assessment and management.

ABCD2 vs 3 and 3-I Scores

A study comparing the performance of the ABCD3 & 3-I scores to the older ABCD2 score found that the newer scores were much more accurate in predicting the risk of stroke following a TIA event. The introduction of new parameters in the 3-I score, specifically dual TIA and carotid stenosis, were found to be significantly associated with the risk of stroke. However, the researchers discovered that the presence of an abnormal diffusion-weighted image (AWI) in MRI exams was not a reliable predictor. [1]

Nevertheless, the new scores demonstrated improved short-term predictability. The authors suggested that including intracranial stenosis as a parameter and excluding AWI would further enhance the predictive ability for stroke, even up to the 3-year mark (resulting in a reclassification improvement of 30.5%, p<0.01). [1] Superiority at predicting the risk of stroke within 3 months was also demonstrated in a study done in 2018. [2]

Another study on 305 patients showed that even though the ABCD3-I and ABCD2 scores have similar specificities, the new score has a much better sensitivity. [3]

More information on the original ABCD2 & 3 scores can be found in another lesson titled ABCD 2&3 Scores.

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Lesson authors: Dr. Mironescu Olivier, Dr. Huțuleac Oana-Mihaela
Published on: 29 Jun 2023 00:06
Open in mediakronos:
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The ABCD3 Score:

The ABCD3 score is a clinical risk stratification tool used to assess the short-term risk of stroke following a transient ischemic attack (TIA). It evaluates five parameters:

  1. Age (A)
  2. Blood pressure (B)
  3. Clinical features (C)
  4. Duration of TIA (D)
  5. Diabetes (D)
  6. Dual TIA (D)

Each parameter is assigned a score ranging from 0 to 2, with a total score ranging from 0 to 7. The higher the score, the greater the risk of stroke. The ABCD3 score helps clinicians identify individuals who require urgent evaluation and intervention to prevent future strokes.

ABCD 3-I Score:

The 3-I score is an enhanced version of the ABCD3 score that incorporates additional parameters for risk assessment. In addition to the original ABCD3 parameters, the 3-I score includes two more parameters:

  • Abnormal DWI (diffusion-weighted image)
  • Ipsilateral stenosis of the carotid artery (I)

These new parameters are associated with an increased risk of stroke following a TIA. By considering these additional factors, the 3-I score provides a more comprehensive risk assessment, allowing for better prediction of stroke risk and potentially influencing treatment decisions.

Use:

Both the ABCD3 and 3-I scores are used by healthcare professionals to evaluate the risk of stroke in individuals who have experienced a transient ischemic attack. These scores assist in the identification of patients who may benefit from urgent intervention, such as initiation of antiplatelet therapy, anticoagulation, or expedited referral to a specialist. The scores help guide clinical decision-making, enabling healthcare providers to prioritize interventions and optimize patient care based on their individual risk profiles.

It's important to note that these scoring systems are tools to aid in risk assessment and should be used in conjunction with clinical judgment and other diagnostic tests. Healthcare professionals will consider various factors, including patient history, physical examination findings, and additional investigations, to make informed decisions regarding the management and treatment of patients at risk of stroke following a TIA.

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