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Child–Turcotte–Pugh calculator for the classification of cirrhosis severity

Child-Pugh classification

Child-Pugh score is a system used to classify the severity of liver disease in patients with cirrhosis. It is based on the patient's laboratory values, presence of ascites and encephalopathy, and their ability to perform daily activities. The score ranges from A (mild) to C (severe) and is used to guide treatment decisions and predict survival.

Sure, the Child-Pugh score is a widely used system for assessing the severity of liver disease in patients with cirrhosis. It takes into account several factors that can indicate the patient's overall health status and prognosis. The factors include:

Laboratory values: The score takes into account the patient's bilirubin, albumin, and prothrombin time (/ INR) levels, which can give an indication of the liver's ability to function.
Presence of ascites: The presence of fluid buildup in the abdomen (ascites) is a sign of advanced liver disease and is taken into account in the score.
Encephalopathy: Encephalopathy is a neurological condition that can occur in patients with advanced liver disease and is characterized by confusion, disorientation, and changes in the level of consciousness.

Based on these factors, patients are assigned a score of A, B, or C, with A indicating mild disease, B indicating moderate disease, and C indicating severe disease. The score can be used to guide treatment decisions, such as whether a patient is eligible for liver transplantation, and to predict survival.

Patients are assigned a score from 5 to 15. A score of 5 to 6 is considered mild disease (Class A), 7 to 9 is considered moderate disease (Class B) and 10 to 15 is considered severe disease (Class C). These classes are associated with patient survival rate, where Class A patients have between 100% and 85% one to two year survival rates, Class B patients have 80% and 60% one-two year survival rates and Class C patients have 45% and 35% one-two year survival rates.

There are alternative scores available, which take into account the patient’s nutritional status or other laboratory values besides coagulation, bilirubin and albumin.

Last update: 23 Jan 2023 01:10

References

1. Assessment of the prognosis of cirrhosis: Child-Pugh versus MELDPDF. François Durand, Dominique Valla. Journal of Hepatology, 42, SUPPL. 1, 4 2005

2. Child-Pugh Classification: Time to Abandon?. Beverley Kok, Juan G. Abraldes. Seminars in Liver Disease, 39, 1, 2019

3. Child-Pugh versus MELD score in predicting survival in patients undergoing transjugular intrahepatic portosystemic shunt. B. Angermayr, M. Cejna et al.. Gut, 52, 6, 6 2003

4. Superiority of the Child-Pugh Classification to Quantitative Liver Function Tests for Assessing Prognosis of Liver Cirrhosis. I. Albers, H. Hartmann et al.. http://dx.doi.org/10.3109/00365528909093045, 24, 3, 2009

5. MELD vs Child-Pugh and creatinine-modified Child-Pugh score for predicting survival in patients with decompensated cirrhosis. George V. Papatheodoridis, Evangelos Cholongitas et al.. World Journal of Gastroenterology : WJG, 11, 20, 5 2005

6. Development of a nomogram to predict outcome after liver resection for hepatocellular carcinoma in Child-Pugh B cirrhosis. Giammauro Berardi, Zenichi Morise et al.. Journal of Hepatology, 72, 1, 1 2020

7. Clarification of risk factors for abdominal operations in patients with hepatic cirrhosis.. R. Neal Garrison, H. M. Cryer et al.. Annals of Surgery, 199, 6, 1984

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Lesson authors: Dr. Mironescu

Published on: 23 Jan 2023 01:10

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Child-Pugh score is a system used to classify the severity of liver disease in patients with cirrhosis. It is based on the patient's laboratory values, presence of ascites and encephalopathy, and their ability to perform daily activities. The score ranges from A (mild) to C (severe) and is used to guide treatment decisions and predict survival.

Sure, the Child-Pugh score is a widely used system for assessing the severity of liver disease in patients with cirrhosis. It takes into account several factors that can indicate the patient's overall health status and prognosis. The factors include:

Laboratory values: The score takes into account the patient's bilirubin, albumin, and prothrombin time (/ INR) levels, which can give an indication of the liver's ability to function.
Presence of ascites: The presence of fluid buildup in the abdomen (ascites) is a sign of advanced liver disease and is taken into account in the score.
Encephalopathy: Encephalopathy is a neurological condition that can occur in patients with advanced liver disease and is characterized by confusion, disorientation, and changes in the level of consciousness.

Based on these factors, patients are assigned a score of A, B, or C, with A indicating mild disease, B indicating moderate disease, and C indicating severe disease. The score can be used to guide treatment decisions, such as whether a patient is eligible for liver transplantation, and to predict survival.

Patients are assigned a score from 5 to 15. A score of 5 to 6 is considered mild disease (Class A), 7 to 9 is considered moderate disease (Class B) and 10 to 15 is considered severe disease (Class C). These classes are associated with patient survival rate, where Class A patients have between 100% and 85% one to two year survival rates, Class B patients have 80% and 60% one-two year survival rates and Class C patients have 45% and 35% one-two year survival rates.

There are alternative scores available, which take into account the patient’s nutritional status or other laboratory values besides coagulation, bilirubin and albumin.

Child, Pugh, Cirrhosis, Severity, Surgery, Liver, Hepatobiliary, Operation, Transplant, Encephalopathy, INR, TP, International, Normalized, Ratio, Coagulation, Digestive, tractChild–Turcotte–Pugh calculator for the classification of cirrhosis severityChild-Pugh classification0000